We report our clinical experience with rituximab in the treatment of 2 patients with idiopathic cutaneous angiitis who relapsed after treatment with high-dose corticosteroids and cyclophosphamide.A 39-year-old woman and a 51-year-old man presented with ulcerating maculopapular rash in both lower limbs which relapsed 6 months after treatment with a
The trigeminal ganglion is implicated in the underlying pathology of migraine and temporomandibular joint disorders (TMD), which are orofacial pain Recliners conditions involving peripheral and central sensitization.The neuropeptide calcitonin gene-related peptide (CGRP) is synthesized in some trigeminal ganglion neurons, and its release promotes i
Goal of this research was to develop and manufacture planetary gearbox prototype using rapid prototyping technology (additive Self Aligning Bearing manufacturing).Developed prototype was used to visually analyse the design of the planetary gearbox.Also, it was used to improve and innovate education of students on several courses at Mechanical Desig
Measuring the performance of food and agricultural systems is critical for their transformation towards a sustainable, healthy, and resilient future.To guide decisions and ensure agrifood systems deliver multiple functions, a holistic systems perspective is needed.Previous reviews of assessment approaches have focused primarily on the farm level an